trfh | Telomeric repeat-binding factor 2

Keyword	CPC	PCC	Volume	Score	Length of keyword
trfh	1.64	0.1	1181	12	4

Keyword	CPC	PCC	Volume	Score
trfh	0.8	0.8	7770	95
trfhx	0.71	0.2	6476	39
trfh obits	0.17	0.3	7809	33
trfhg	0.99	0.7	3236	75
trfhj	1.61	0.3	3055	82
trfhyey canjv	1.76	0.5	3096	94
trophy	0.53	0.2	1877	36
trfhf	0.42	0.4	5278	66
trfhb	0.61	0.1	7011	76
trfht	1.58	0.6	8726	79
trfhn	0.1	1	9232	53
trfghjk	0.08	0.3	4968	81
trfhgf	1.61	0.2	9394	19
trfhu	0.66	0.8	1883	43
trfhd	0.1	0.6	9071	70
trfhtr	0.71	0.4	5238	95
trfhui vnshbv	0.52	0.1	2922	8
trfhduc	1.42	0.7	9849	24
trfhye canjv	0.47	0.9	7854	91
trfhui srnu eurtbhu	0.03	0.2	71	39

Search Results related to trfh on Search Engine

Telomeric repeat-binding factor 2 - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Telomeric_repeat-binding_factor_2

WEBFunction. T-Loop formation. ATM kinase prevention. TERF2 Knockout Effects. Interactions. Disease relevance of TERF2. Cancer. References. Further reading. External links. Telomeric repeat-binding factor 2 is a protein that is …

DA: 94 PA: 20 MOZ Rank: 92

TRFH domain: at the root of telomere protein evolution? - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752847/

WEBDec 1, 2017 · These studies concerning both mammalian and Schizosaccharomyces pombe proteins reveal unexpected structural conservation of a motif called TRFH (Telomeric Repeat Factors Homology) domain between several subunits in these complexes, providing a rationale for further dissection of the role of telomeres in chromosome stability, aging …

DA: 5 PA: 14 MOZ Rank: 11

TRFH domain: at the root of telomere protein evolution?
nature.com

https://www.nature.com/articles/cr2017152

WEBDec 1, 2017 · article. Research Highlight. Published: 01 December 2017. TRFH domain: at the root of telomere protein evolution? Marie-Joseph Giraud-Panis, Jing Ye & Eric Gilson. Cell Research 28 , 7–8 ( 2018)...

DA: 5 PA: 28 MOZ Rank: 32

Structure of the TRFH Dimerization Domain of the Human …
cell.com

https://www.cell.com/fulltext/S1097-2765(01)00321-5

WEBAbstract. TRF1 and TRF2 are key components of vertebrate telomeres. They bind to double-stranded telomeric DNA as homodimers. Dimerization involves the TRF homology (TRFH) domain, which also mediates interactions with other telomeric proteins.

DA: 91 PA: 95 MOZ Rank: 98

Structure of the TRFH dimerization domain of the human …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/11545737/

WEBPMID: 11545737. DOI: 10.1016/s1097-2765 (01)00321-5. Abstract. TRF1 and TRF2 are key components of vertebrate telomeres. They bind to double-stranded telomeric DNA as homodimers. Dimerization involves the TRF homology (TRFH) domain, which also mediates interactions with other telomeric proteins.

DA: 28 PA: 67 MOZ Rank: 54

CDD Conserved Protein Domain Family: TRFH - National Center …
nih.gov

https://www.ncbi.nlm.nih.gov/Structure/cdd/cd00280

WEBOct 2, 2020 · Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability, protecting the chromosome ends from degradation and end-to-end fusion.

DA: 45 PA: 46 MOZ Rank: 56

Irreversible inhibition of TRF2TRFH recruiting functions ... - Cell …
cell.com

https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00423-3

WEBDec 7, 2023 · Mutations in the TRF2 TRFH domain physically impair t-loop formation and prevent the recruitment of several factors that promote efficient telomere replication, causing telomeric DNA damage. Here, we design, synthesize, and biologically test covalent cyclic peptides that irreversibly target the TRF2 TRFH domain.

DA: 14 PA: 94 MOZ Rank: 71

TRF2 recruits ORC through TRFH domain dimerization
sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S0167488916302907

WEBJan 1, 2017 · Cite. https://doi.org/10.1016/j.bbamcr.2016.11.004 Get rights and content. Under an Elsevier user license. open archive. Highlights. •. TRF2 is thought to mediate ORC recruitment to the telomeric replication origins. •. Tethering of TRF2 by LacI fusion to a lacO array induces ORC recruitment. •.

DA: 64 PA: 25 MOZ Rank: 79

TRFH domain: at the root of telomere protein evolution?
nih.gov

https://pubmed.ncbi.nlm.nih.gov/29192673/

WEBThese studies concerning both mammalian and Schizosaccharomyces pombe proteins reveal unexpected structural conservation of a motif called TRFH (Telomeric Repeat Factors Homology) domain between several subunits in these complexes, providing a rationale for further dissection of the role of telomeres in chromosome stability, aging …

DA: 94 PA: 83 MOZ Rank: 68

Structure of the TRFH Dimerization Domain of the Human …
sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S1097276501003215

WEBAug 1, 2001 · Dimerization involves the TRF homology (TRFH) domain, which also mediates interactions with other telomeric proteins. The crystal structures of the dimerization domains from human TRF1 and TRF2 were determined at …

DA: 82 PA: 14 MOZ Rank: 88